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On top of that, adoptive T cellular therapies like posoleucel also purpose LMP2 coupled with other latency proteins one example is EBNA1, reinforcing its value as remaining a conserved and immunodominant antigen.
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Therapeutic vaccine candidates employing viral vectors encoding LMP2 have properly induced virus-certain CD8⁺ T cell responses in early-stage scientific trials. Also, adoptive T mobile therapies like posoleucel also goal LMP2 together with other latency proteins such as EBNA1, reinforcing its importance for a conserved and immunodominant antigen.
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